MIT Biologists Discover Cellular Pathway that Triggers Colon Cancer Spread
Researchers found that blocking YAP1 or ceramide production cut liver metastases in mice and linked higher BMI to stronger YAP1 activity.
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4 Articles
Study Reveals How Dietary Fat May Help Colorectal Cancer Spread
THE BRONX, N.Y., Sept. 24, 2026 /PRNewswire/ -- Metastasis—the spread of cancer from a primary tumor to other parts of the body—causes most cancer-related deaths. But how primary tumor cells gain this deadly ability to spread remains largely unknown. Now,…
MIT biologists discover cellular pathway that triggers colon cancer spread
Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.
High-fat diet activates cellular repair pathway that helps colon cancer spread
Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.
Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases
Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.
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