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More Middle-Class Americans Sell Plasma Amid Financial Pressure

In 2025, U.S. donors sold $4.7 billion worth of plasma, aiding household finances amid rising costs and job instability, with much plasma exported globally.

  • Plasma donation, historically more common among lower-income individuals, is increasingly attracting a wider range of donors, including suburban residents and working professionals coping with rising living costs.
  • Plasma is essential for producing treatments for immune disorders and other serious medical conditions, and global demand for it remains high.
  • The United States supplies most of the world’s plasma products, and federal regulations permit individuals to donate up to twice a week under established health and safety guidelines.
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More than 200,000 people a day attend paid donation centers in the United States, in a market that generated $4.7 billion in 2024.

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NBC Dallas-Fort Worth broke the news in Fort Worth, United States on Thursday, February 12, 2026.
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