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Metformin Activates Tumor-Fighting T Cells in Mice, Suggesting Potential Role in Cancer Immunotherapy - Gilmore Health News

Summary by Gilmore Health News
Key Takeaways Metformin boosted CD8+ T cell activity in mice by increasing mitochondrial ROS and promoting immune cell growth. The anti-tumor effect wasn’t due to apoptosis, but to immune system modulation via interferon-γ secretion. Findings are preclinical — no human data yet, and the study didn’t test interactions with real-world cancer treatments. A team of  Okayama University scientists just helped shed light on an often proposed but poorly…
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Metformin Activates Tumor-Fighting T Cells in Mice, Suggesting Potential Role in Cancer Immunotherapy - Gilmore Health News

Key Takeaways Metformin boosted CD8+ T cell activity in mice by increasing mitochondrial ROS and promoting immune cell growth. The anti-tumor effect wasn’t due to apoptosis, but to immune system modulation via interferon-γ secretion. Findings are preclinical — no human data yet, and the study didn’t test interactions with real-world cancer treatments. A team of  Okayama University scientists just helped shed light on an often proposed but poorly…

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Gilmore Health News broke the news in on Friday, March 28, 2025.
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