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MERS-Like Bat Viruses Could Cross Into Humans After Single Mutation
- A study published on June 4, 2025, by researchers from Washington State University and partner institutions analyzed bat viruses related to MERS-CoV to assess spillover risk to humans.
- The research focused on merbecoviruses, particularly the HKU5 subgroup, which has been identified in regions including Asia, Europe, Africa, and the Middle East, and was found to utilize the ACE2 receptor associated with SARS-CoV-2 infection in humans.
- The study found HKU5 viruses currently bind poorly to human ACE2, but mutations in their spike protein may allow them to infect humans, posing a possible pandemic threat.
- Michael Letko, lead virologist, highlighted that HKU5 viruses could be close to acquiring the ability to infect humans, underscoring the need for continued monitoring despite no current evidence of human infection.
- This research highlights the importance of proactive monitoring and investment in One Health initiatives globally to prevent zoonotic pandemics and improve pandemic preparedness.
31 Articles
31 Articles
Scientists warn of new virus discovered in China being 'one small step' away from triggering a pandemic
A newly identified coronavirus, HKU5-CoV-2, discovered in bats in China, has sparked alarm among scientists due to its potential to trigger a global pandemic. American researchers warn that this virus, closely related to the deadly Middle East Respiratory Syndrome (MERS), is just one small mutation away from being able to infect humans and cause widespread […]
As soon as the controversial WHO pandemic agreement has been concluded, the media machine is stirring up new panic. This time, two viruses from China are in the focus: the new Coronavirus strain HKU5-CoV-2 and an outbreak of the well-known Human Metapneumovirus (HMPV). While experts are warning of a possible catastrophe, critics ask: Is this the next orchestrated fear policy? It seems determined to keep the population in constant alertness. The …
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