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Maine’s Patrick Dempsey Takes on the Role of a Killer in New Fox Series
Patrick Dempsey returns to network TV after 10 years portraying a hitman with early-onset Alzheimer’s, exploring a complex role that contrasts his previous characters.
- On Sunday, Maine native Patrick Dempsey premiered the Fox series Memory of a Killer, his first network TV series in over ten years, airing Mondays at 9 p.m. and streaming on Hulu.
- Explaining his choice, Dempsey said he wanted to explore a darker side he had struggled to express and told the New York Times recently he wanted to test himself.
- The first episode establishes Dempsey as a hired assassin, widower, and devoted father confronting early-onset Alzheimer’s, with Odeya Rush as his grown-up daughter in Hudson Springs, filmed in Perry Point, Ontario, Canada.
- His representatives said Dempsey was not available to speak with the Press Herald, and his Maine philanthropy—including the Dempsey Center and the annual Dempsey Challenge—could boost local interest.
- Known for Grey’s Anatomy, Dempsey rose to fame as Dr. McDreamy and brings varied experience including racing and a 2023 role in Ferrari, handling intense chase scenes in the new show.
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Meet the Cast of Fox’s ‘Memory of a Killer’: Who Does Patrick Dempsey Play?
Memory of a Killer premiered in January with Patrick Dempsey embodying one of his most complex roles to date. But who does he play on the Fox series? Dempsey portrays lead character Angelo Doyle/Flannery, who is “leading a dangerous double life while hiding an even deadlier person secret — he has developed early onset Alzheimer’s,” according to a Fox press release issued in July 2025. The show, which is inspired by the book De Zaak Alzheimer, is…
·United States
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Central Maine NewsReposted by 
Portland Press Herald
Portland Press HeraldMaine’s Patrick Dempsey takes on the role of a killer in new Fox series
In 'Memory of a Killer,' the actor known as McDreamy on the long-running 'Grey's Anatomy' is an assassin for hire leading a double life and battling dementia. The series premiered Jan. 25.
·Maine, United States
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Total News Sources36
Leaning Left2Leaning Right3Center16Last UpdatedBias Distribution76% Center
Bias Distribution
- 76% of the sources are Center
76% Center
C 76%
14%
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