Megabase-Scale Precision Genome Editing Achieved in Eukaryotic Cells

Scientists just cracked the code to editing entire chromosomes flawlessly

A group of Chinese scientists has created powerful new tools that allow them to edit large chunks of DNA with incredible accuracy—and without leaving any trace. Using a mix of advanced protein design, AI, and clever genetic tweaks, they’ve overcome major limitations in older gene editing methods. These tools can flip, remove, or insert massive pieces of genetic code in both plants and animals. To prove it works, they engineered rice that’s resis…

Scientists achieve megabase-scale precision genome editing in eukaryotic cells

A team led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems to achieves multiple types of precise DNA manipulations ranging from kilobase to megabase scale in higher organisms, especially plants.

Programmable Chromosome Engineering systems enable precise DNA manipulations

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

Megabase-scale precision genome editing achieved in eukaryotic cells

A team of Chinese researchers has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

Chinese Researchers Develop Breakthrough Megabase-Scale Genome Editing Technologies

A team of scientists led by Prof. GAO Caixia at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, has developed two innovative genome editing platforms known as Programmable Chromosome Engineering (PCE) and RePCE. These technologies enable highly precise DNA manipulations at scales ranging from kilobases to megabases in plants and other eukaryotic cells. Published online in Cell on August 4, the study overcomes lo…

Scientists achieve megabase-scale precision genome editing in eukaryotic cells - Scientific Inquirer

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems. The study, published online in Cell on August 4, achieves multiple types of precise DNA manipulations ranging from kilobase to megabase scale in higher organisms, especially plant…