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Congo Faces Unprecedented Ebola Outbreak without Approved Vaccine Protection

WHO allocated 20,000 doses for the research vaccination program as officials seek evidence on Ervebo’s protection against Ebola Bundibugyo virus.

  • On Saturday, Médecins Sans Frontières launched a vaccination campaign in Ituri province targeting 20,000 frontline health workers to test whether Ervebo offers cross-protection against the Bundibugyo Ebola virus.
  • The current Bundibugyo outbreak is the largest in Democratic Republic of the Congo history, with no approved vaccine available, and has infected more than 7,670 people and killed nearly 3,700.
  • Although Ervebo is highly effective against Zaire Ebola, the World Health Organization says evidence on its protection against Bundibugyo remains "limited and inconclusive."
  • Guyguy Manangama, an epidemiologist and deputy director of Congo Ebola operations with MSF, called the initiative a "race against time," noting that even partial protection could reduce severe illness and death.
  • The Coalition for Epidemic Preparedness Innovations is funding additional Bundibugyo vaccine candidates, including Moderna's mRNA-1469 and the University of Oxford's ChAdOx1 BDBV, to address long-term investment gaps.
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The enormous Central African country is going through the most deadly Ebola epidemic in its history. Declared in May, it has already caused 3,639 deaths and infected 7,541 people, according to the latest report of the National Institute of Public Health released on Saturday. The epidemic is caused by the Bundibugyo strain of the virus, for which there is no specific immunizer or treatment so far, although there are two vaccines in clinical trial…

·Issy-les-Moulineaux, France
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UN News broke the news in New York, United States on Monday, September 21, 2026.
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