Prenatal High Fructose Exposure Impairs Brain Development and Memory
Researchers found the diet caused persistent epigenetic changes in fetal neural stem cells, and restoring gene expression partially recovered stem cell function.
4 Articles
4 Articles
High Fructose During Pregnancy Impairs Stem Cell Function in the Fetal Brain — International Society for Stem Cell Research
Nutritional imbalance during pregnancy can have long-lasting effects on the health status and disease susceptibility of the offspring. As such, high fructose intake through sweetened food and beverages in pregnant women has been associated with an increased susceptibility to diabetes and cardiovascular disease, as well as neurological and cognitive impairments in the offspring. Currently, it is not well understood how early life exposure to fruc…
Maternal High-Fructose Diets Epigenetically Scar Fetal Brain Cells
A maternal diet high in fructose corn syrup programs permanent learning and memory deficits in adult offspring. The mechanism is driven by lasting epigenetic imprints on fetal neural stem cells that silence neurogenesis genes into adulthood, establishing a direct "biological memory" of prenatal maternal nutrition.

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