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Philly Scientists Win 2026 Breakthrough Prize for Developing Gene Therapy for Blindness

Summary by Hastings Tribune
Three Philadelphia scientists won a $3 million Breakthrough Prize for developing the first FDA-approved gene therapy for a genetic disease, prize sponsors announced Saturday.

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The Breakthrough Prize Foundation announced, this Saturday, the winners of the 14th edition of the award, considered the Science Oscar of 2026. In the category of Life Sciences, a couple was graduated by the development of the first genetic therapy approved in the United States for a disease that causes total blindness. The winners receive R$ 3 million, the equivalent of about R$ 15 million in the current rating.

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With the help of a new gene therapy, those affected by a rare eye disease can regain some of their vision. Three scientists were awarded for this discovery on the weekend.

Why is a child sometimes born blind? Very often, a genetic disorder called Leber congenital amaurosis, also known by the abbreviation LCA, is to blame. Until recently, this was a diagnosis that gave such children no hope. Two people, who took a quarter of a century to do it, have changed that. Now, molecular biologist Jean Bennett and ophthalmologist Albert Maguire have received the prestigious Breakthrough Prize and a reward of three million do…

Jean Bennett and Albert Maguire, along with Katherine High, have won the prestigious Breakthrough Prize for developing Luxturna, a treatment the couple have worked on for 25 years that can cure hereditary blindness.

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arcamax.com broke the news on Sunday, April 19, 2026.
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