In Vivo Screen of Plasmodium Targets for Mosquito-Based Malaria Control

In vivo screen of Plasmodium targets for mosquito-based malaria control

The decline in malaria deaths has recently stalled owing to several factors, including the widespread resistance of Anopheles vectors to the insecticides used in long-lasting insecticide-treated nets (LLINs)1,2. One way to mitigate insecticide resistance is to directly kill parasites during their mosquito-stage of development by incorporating antiparasitic compounds into LLINs. This strategy can prevent onward parasite transmission even when ins…

American researchers believe that the patient should receive antimalarial medicines to eliminate the infection so that it can no longer spread the disease. Malaria parasites, which kill nearly 600,000 people per year, most of the children...

Malaria control strategy that efficiently kills parasites in the mosquito could lead to more effective bed nets

A potent combination of antimalarial compounds added to bed nets blocked parasite transmission in mosquitoes while circumventing insecticide resistance, according to a new study led by researchers at Harvard T.H. Chan School of Public Health. The finding dramatically expands understanding of druggable targets in mosquito-stage parasite development and lays the groundwork for a new, more effective way to prevent malaria transmission.

A scientific team has developed a new malaria control strategy that effectively kills parasites in mosquitoes and could lead to more effective mosquito nets. Specifically, researchers at Harvard University have identified 22 potent compounds that inhibit the development of the parasite Plasmodium falciparum in mosquitoes that transmit it. [...] The entry Approach to malaria control opens the door to more effective mosquito nets was first publish…

In Vivo Screen Identifies Mosquito Malaria Targets

In an era where malaria continues to devastate millions of lives worldwide, innovative strategies to curb the transmission of this deadly disease are crucial. A groundbreaking study has now revealed promising advances in the development of next-generation long-lasting insecticidal nets (LLINs) embedded with novel compounds that demonstrate remarkable efficacy against the malaria parasite within mosquitoes. These findings hold transformative pote…

Advancing Novel Malaria Prevention

Advancing Novel Malaria Prevention Image Jessica Martinez Wed, 05/21/2025 - 11:08 SwRI collaborates with Harvard, Oregon Health & Science University to fabricate novel bed nets to target Plasmodium parasites /newsroom/press-releases/swri-fabricates-bed-netting-prototypes-target-malaria-… Hero Landing Title SwRI fabricates bed-netting prototypes to target malaria-causing parasites