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Main Street Social House bringing new energy to Downtown Hannibal

Summary by Muddy River News
HANNIBAL – The building at 422 North Main St. in Downtown Hannibal has long been more than just another storefront. It is one of downtown’s anchors, a massive historic space that generations have driven past, worked in, gathered in and remembered. For the last year, people watched it sit quiet once again. Now, Darrell and Jamie McCoy are bringing it back to life. Main Street Social House, formerly home to Mark Twain Brewing Company and later Fri…
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Muddy River News broke the news on Monday, May 25, 2026.
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