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Madison Is the 40th-Best Large City in the U.S. to Start a Business (2026)

The study compared startup opportunities in 100 large U.S. cities using 19 metrics, including five-year business survival rate and labor costs.

  • Madison, Wis., ranked as the 40th-best large city in the U.S. to start a business, according to a WalletHub study comparing startup opportunities across 100 cities using 19 key metrics.
  • The methodology evaluated cities using metrics including five-year business survival rates, labor costs, and office-space affordability to determine startup viability and growth potential.
  • WalletHub analyst Chip Lupo warned that "one in every five startups doesn't make it past the first year," emphasizing the need for supportive city environments with capital and workers.
  • Tampa took the top spot with a score of 64.15, while St. Pete ranked fifth, and Washington, D.C., was identified as the worst-ranked city for new businesses.
  • The granular data on specific metrics allows Madison stakeholders to identify weaknesses in business costs, resource access, and environment factors to address through funding and policy priorities.
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Bias Distribution

  • 87% of the sources are Center
87% Center

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Bulletin-Review broke the news on Monday, April 20, 2026.
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