Machine Learning Modeling Identifies Hypertrophic Cardiomyopathy Subtypes with Genetic Signature

Machine Learning Modeling Identifies Hypertrophic Cardiomyopathy Subtypes with Genetic Signature

Researchers from Tongji Medical College, Huazhong University of Science and Technology, et al. recruited two HCM cohorts, followed the first for ~32.8 months, identified two HCM subtypes via echocardiography clustering, proposed a phenotype-genotype analysis method, found 46 subtype-predicting genes, verified results in the second cohort, and concluded HCM classification via echocardiography and the 46-gene screening.