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LSD shows promise for reducing anxiety in drugmaker’s midstage study

MindMed published a study on Sept. 4 showing a single dose of pharmaceutical LSD eased anxiety symptoms among nearly 200 adults with generalized anxiety disorder.
Researchers tested several doses under professional supervision without extended talk therapy to isolate LSD's effects on moderate-to-severe anxiety.
After four weeks, those administered the top two dosage levels exhibited notably reduced anxiety levels relative to individuals given lower doses or a placebo.
By 12 weeks, nearly 48% of patients given LSD were in remission versus 20% with placebo, and 65% taking the 100 milligram dose still showed improvements.
MindMed is currently running two expanded advanced-phase studies with extended patient follow-up, and may pursue FDA approval if the findings continue to be positive, while lead author Dr. Fava mentioned that some patients could require additional treatments.

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