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Low-Dose Methotrexate Fails to Treat Inflammatory Knee Osteoarthritis

Summary by JAMA Network
Although low-dose methotrexate reduces inflammation for patients with rheumatoid arthritis, a randomized clinical trial found that it did not relieve pain for patients with inflammatory knee osteoarthritis.

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JAMA Network broke the news in on Tuesday, July 22, 2025.
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