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Leveraging Statistical Data Monitoring to Detect Fraud in Clinical Trials
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Leveraging Statistical Data Monitoring to Detect Fraud in Clinical Trials
Ensuring data integrity in clinical trials is crucial, as emphasized by the International Council for Harmonization’s E6 (R3) guidelines. This article delves into the role of statistical data monitoring in identifying potential data manipulation, highlighting the effectiveness of various statistical tests for continuous variables in detecting deliberate data falsification. Fraud in clinical trials often involves subtle manipulations to avoid det…
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