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Random Drug Test Leads to Cancer Diagnosis for Standout NFL Linebacker

Alex Singleton, leading the Broncos with 89 tackles, had surgery after early-stage testicular cancer diagnosis and expects to return soon, officials said.

  • Denver Broncos inside linebacker Alex Singleton said Wednesday he underwent successful surgery Friday for testicular cancer after being diagnosed last week following the Nov. 6 win over the Las Vegas Raiders.
  • A little over two weeks ago, a random NFL drug test showed Singleton had elevated hCG, prompting ultrasounds and confirmation by Dr. Geoff Ledgerwood and Dr. Andrew Zilavy last week.
  • On the field, Singleton logged all 60 defensive snaps and leads the Broncos with 89 tackles in 10 games, marking a major loss for Denver Broncos defense while he recovers.
  • He expects to return to the field in the coming weeks while awaiting more tests; the Broncos and Sean Payton said Singleton's health is their priority and the cancer appears caught early.
  • He shared the news first with teammates and coaches before a public post, thanking the Broncos organization, Paul Sheehy, Sam, and family for support as he urged early detection.
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TMZ broke the news in Los Angeles, United States on Monday, November 10, 2025.
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