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Kyverna rises on stiff person syndrome data

Kyverna’s mivocabtagene autoleucel showed a median 46% walking improvement and 81% of patients exceeded a 20% clinically meaningful threshold in a 26-patient Phase 2 trial.

Summary by Pharmaphorum
Kyverna hopes to file CAR-T therapy miv-cell for approval as the first therapy for stiff person syndrome, a rare and debilitating autoimmune disease.

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biopharmadive.com broke the news in on Monday, December 15, 2025.
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