B.C. Researcher Helps Discover New Drug-Resistant West African Parasitic Worm
- A research team led by Dr. Abhinaya Venkatesan discovered a new drug-resistant roundworm species, Trichuris incognita, in West Africa.
- The discovery followed reports that the WHO-recommended drug combination ivermectin and albendazole was less effective in Côte d'Ivoire than in Tanzania and Laos.
- The team applied genomic analysis to detect variations within the parasite group after treatment failure raised concerns about resistance developing from prolonged anthelmintic use.
- The treatment demonstrated a 98% efficacy in trials conducted in Tanzania and Laos, but its effectiveness dropped below 70% in Côte d'Ivoire, leading the WHO to reconsider treatment approaches amid slow progress in new drug development.
- The discovery suggests the need for further research on new drugs and the global spread of resistant parasites to adapt public health strategies effectively.
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B.C. researcher helps discover new drug-resistant West African parasitic worm
Study led by Surrey-based researcher at KPU’s Applied Genomics Centre
·Salmon Arm, Canada
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