Japanese Scientists Discover Garlic May Help Slow Aging
The compound boosted muscle strength and reduced frailty in aged mice, while a human study found higher circulating eNAMPT levels.
- Tokyo-Based researchers from the Institute for Research on Productive Aging and Wakunaga Pharmaceutical identified that S1PC, a compound in aged garlic extract, promotes inter-organ communication to enhance muscle strength in aging.
- Study author Kiyoshi Yoshioka explained that S1PC activates the SIRT1 pathway, promoting secretion of eNAMPT from fat tissue, which travels through the bloodstream to the hypothalamus to regulate muscle function.
- Long-Term administration of S1PC in aged mice reduced frailty scores and increased skeletal muscle force, while human studies showed S1PC increased eNAMPT levels in circulation, particularly in individuals with sufficient fat tissue.
- IRPA Chairman Dr. Shin-ichiro Imai said, "Our findings present a previously unrecognised and unique function of S1PC in activating LKB1," suggesting the compound could become a daily supplement for muscle strength.
- Published in Cell Metabolism, the research will be presented at a Florida conference next month, though further research is needed to evaluate the long-term effects of S1PC on human muscle function.
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Japanese scientists discover garlic may help slow aging
Scientists say It could be used as a daily supplement to improve muscle frailty and general fitness in older people.
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