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Ipsen to Acquire Memo Therapeutics AG, Adding First-in-Class BK Polyomavirus Antibody, Expanding Rare Disease Portfolio

The deal includes a 200 million euro upfront payment and could top 700 million euro if development and sales milestones are met.

  • On Wednesday, Ipsen announced a definitive agreement to acquire Memo Therapeutics AG, focusing on potravitug, a first-in-class monoclonal antibody targeting BK polyomavirus in kidney transplant recipients.
  • BK polyomavirus reactivation affects approximately 30% of kidney transplant patients within the first year, yet no approved targeted therapies exist, forcing clinicians to reduce immunosuppression and risking graft rejection.
  • The Phase II SAFE KIDNEY II trial demonstrated potravitug's efficacy, with biopsy-proven BK polyomavirus associated nephropathy declining from 51.2% to 31.6% in the treatment group by week 20, versus no change in placebo.
  • Shareholders of Memo Therapeutics AG will receive €200 million at closing, with deferred payments pushing total potential consideration above €700 million, expected during Q3 2026 subject to customary conditions.
  • Ipsen plans to initiate the SAFE KIDNEY III trial later this year, while Memo Therapeutics AG transfers unrelated assets including the DROPZYLLA platform to a newly incorporated company, Memorises Bio.
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Ipsen to acquire Memo Therapeutics AG, adding first-in-class BK polyomavirus antibody, expanding rare disease portfolio

Acquisition focused on clinical-stage program potravitug, a first-in-class BK polyomavirus monoclonal antibody

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NiagaraFallsReview.ca broke the news in Niagara Falls, Canada on Wednesday, July 1, 2026.
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