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Ipsen presents first-in-class late-breaking Phase II corabotase data in glabellar lines showing sustained duration of effect reinforced by consistently high patient satisfaction
Ipsen said 60.8% of patients on corabotase had sustained effect at Week 24, with 82.8% reporting satisfaction.
On Saturday, May 16, 2026, Ipsen presented the first corabotase data for moderate-to-severe glabellar lines at the Scale Symposium in Nashville, TN, involving 183 patients.
Corabotase is an investigational recombinant neuroinhibitor, or RNITM, designed to increase receptor affinity and improve resistance to degradation for sustained muscle inhibition.
At Week 24, 60.8% of patients treated with corabotase experienced sustained effect versus 36.7% for Dysport, with 82.8% rating satisfaction as "very satisfied" or "satisfied."
Patients treated with corabotase showed a rapid onset of action of 0.84 days, with 66% demonstrating significant improvement at Week 4 compared to 0% with placebo.
Professor of Dermatology Martina Kerscher noted the initial data are encouraging as Ipsen evaluates corabotase across three aesthetic indications in the LANTIC trial.