Bispecific Antibodies in the Treatment of Multiple Myeloma

Bispecific antibodies in the treatment of multiple myeloma

The treatment paradigm in myeloma is constantly changing. Upfront use of monoclonal antibodies like daratumumab along with proteasome inhibitors (PI)s, and immune modulators (IMiD)s have significantly improved survival and outcomes, but also cause unique challenges at the time of relapse. Engaging immune T cells for tumour cell kill with chimeric antigenic T-cell (CAR T-cell) therapy and bispecific antibodies have become important therapeutic op…

Investigational treatment shows promise for aggressive multiple myeloma

Results suggest bispecific antibody combination could improve outcomes