Switch to Tirzepatide in T2D More Effective Than Upping Dulaglutide Dose

Switch to Tirzepatide in T2D More Effective Than Upping Dulaglutide Dose

(MedPage Today) -- Diabetes patients on dulaglutide (Trulicity) had better glycemic control and more weight loss if they switched to tirzepatide (Mounjaro) rather than increasing the dose of the earlier-generation GLP-1 receptor agonist, an open...

Doctors are being urged to rethink their approach to diabetes management after a study found that a worrying number of patients newly diagnosed with type 2 diabetes go off their medication within the first year. The research highlights the importance of a personalized, collaborative approach between doctors and patients and suggests innovative solutions, such as glucose monitors and the GEM lifestyle program, have shown promising results in diab…

Switching to Tirzepatide Shows Greater Benefit Than Escalating Dulaglutide in T2D, Obesity

Patients switching to tirzepatide had greater improvements in HBA1C and weight at week 40 in a phase 4 RCT.

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For patients with inadequately controlled type 2 diabetes, switching to tirzepatide improves glucose control and increases weight loss more so than maximizing dulaglutide dose.

Switching from dulaglutide to tirzepatide improves HbA1c reduction in type 2 diabetes

For patients with inadequately controlled type 2 diabetes receiving dulaglutide, switching to tirzepatide is associated with additional hemoglobin A1c (HbA1c) reduction and weight loss compared with escalating treatment with dulaglutide, according to a study published online April 4 in the Annals of Internal Medicine to coincide with the Internal Medicine Meeting, the annual meeting of the American College of Physicians, held from April 3 to 5 i…

Switching to Tirzepatide Outweighs Upping Dulaglutide Dose

The study finds better A1c lowering and weight reduction, but an expert clinician says practical issues may pose barriers. Medscape Medical News