An up and coming Indigenous two-spirit comedian is using her own brand of humour to tackle serious issues. Janelle Niles is of Mi’kmaq heritage and originally from Nova Scotia but has called Ottawa home for the past two decades. Earlier this week, she was performing at the city’s National Arts Centre. “Well I always wanted to be a standup comedian since I was like 14-years-old and I was watching Richard Pryor and Paul Mooney and they tackled tho…