Multivariate Genome-Wide Analysis of Aging-Related Traits Identifies Novel Loci and New Drug Targets for Healthy Aging
- A 2024 study identified two distinct molecular aging shifts in humans, occurring around age 44 and the early 60s, marking dramatic body changes.
- Researchers ruled out menopause as the main cause for mid-40s changes, noting that social isolation quietly impacts both body and mind.
- The study found taurine levels decline with age in animals and humans but showed no clear link to health status, requiring further human trials.
- Taurine extended mice lifespan by 10–12 percent, yet Dr. Pieter Cohen said taurine supplements aren’t ready for prime-time without more human studies.
- These findings suggest aging involves sudden molecular changes and that lifestyle factors like exercise may influence biomarkers, but more research is needed.
13 Articles
13 Articles
Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging
The concept of aging is complex, including many related phenotypes such as healthspan, lifespan, extreme longevity, frailty and epigenetic aging, suggesting shared biological underpinnings; however, aging-related endpoints have been primarily assessed individually. Using data from these traits and multivariate genome-wide association study methods, we modeled their underlying genetic factor (‘mvAge’). mvAge (effective n = ~1.9 million participan…
Research done by Tanford University has revealed that the average age of a person increases rapidly between the ages of 44 and 60. Know why biological changes occur at these two ages and how to prevent them.
13 Surprising Habits That Quietly Age You Faster, According to Experts
Fact checked by Nick BlackmerHalfpoint Images / Getty Images Some habits like lack of exercise, eating ultra-processed foods, and too much tech time can make you age faster.Your genes only account for a small portion of your life expectancy.Instead, the choices you make every day and the things you prioritize will have a greater influence on how long you live.Here are some choices or habits that could be quietly aging you.1. Never Taking a Day O…
Ageing in two different stages? Recently, a genetic study conducted by a Stanford Medicine team, led by geneticist Michael Snyder, has shown that there are two defined stages where aging accelerates markedly. In this article we will tell you all the details of the research.
By analyzing several thousand samples taken from 100 volunteers followed over two years, scientists have shown that aging is far from being a progressive phenomenon. At two specific moments in life, it accelerates. Results that leave the body of the...
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