How Metabolic Chatter Between Cells Undermines Anti-Tumor Immunity

How prostate cancer turns immune cells into traitors

Scientists have revealed how certain immune cells may be quietly helping prostate cancer grow—and how blocking them could help the body fight back. The study in Molecular Cancer Research identifies a group of cells called macrophages that, instead of protecting the body, appear to shield tumors from attack and promote tumor metastasis. These cells are typically the immune system’s housekeeping crew—engulfing dead cells and responding to infectio…

How Metabolic Chatter Between Cells Undermines Anti-Tumor Immunity

A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary metabolic processes, program one set of noncancerous cells to manipulate another set of such cells to support their growth and survival.