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With No Initial DNA Match, Guthrie Investigators Turn to One of Their Newest Tools to Crack Cases: Genetic Genealogy

Pima County investigators use genetic genealogy to identify a male DNA profile from a glove not found in FBI databases, seeking relatives to locate a suspect.

  • On Tuesday, Pima County Sheriff's Department said investigators are inputting DNA from Nancy Guthrie, 84-year-old missing woman, into genetic genealogy databases after her February 1 disappearance.
  • Lab results show DNA collected so far did not match any entries in CODIS, and the glove found roughly two miles from Nancy Guthrie's Tucson home holds male DNA with no FBI database hits.
  • Surveillance video shows a masked suspect with a unique gun holster; Nanos said Google, Meta and Apple are helping retrieve more Nest footage and investigators noted a visible ring.
  • Sheriff Chris Nanos said the Guthrie family is cleared as suspects, the case remains active with thousands of tips, and the FBI and Tucson Crime Stoppers offer $100,000 and $102,500 rewards.
  • While genetic genealogy has helped solve high-profile cases, experts say identification speed depends on ancestry and database access, with Moore stating, 'If they have deep roots in the United States, it could be minutes, it could be a few hours.
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With no initial DNA match, Guthrie disappearance investigators turn to one of their newest tools to crack cases: genetic genealogy

Only a few years ago, Tuesday’s announcement that a glove believed to be connected to the disappearance of Nancy Guthrie in Tucson, Arizona, had no match to a DNA database would have been a dead end. Now for investigators, it is just the beginning.

·Atlanta, United States
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Internewscast broke the news in on Wednesday, February 18, 2026.
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