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Gut Microbiome Changes May Signal Parkinson's Disease Risk
- University College London researchers identified a distinct gut "microbial signature" that serves as a "warning signal" for Parkinson's disease years before motor symptoms appear.
- The study analyzed data from 271 Parkinson's patients, 43 GBA1 variant carriers with no symptoms, and 150 healthy controls, revealing an "intermediate" microbiome profile in at-risk individuals.
- Researchers corroborated findings across cohorts in Korea, Turkey, and London, totaling 638 Parkinson's patients and 319 healthy controls, proving the microbial signature's consistency across cultures.
- Co-Lead author Professor Stanislav Dusko Ehrlich said gut analysis could enable doctors to "identify individuals who are at risk," allowing early dietary interventions to reduce Parkinson's risk.
- While promising, the microbiome is "one piece of a complex puzzle" involving genetics and environment; trials are testing whether targeting these pathways can slow Parkinson's progression.
23 Articles
23 Articles
Researchers have just discovered a very specific signature of intestinal microbiota in people affected by Parkinson's disease. What is the link between the intestine and the brain? Dr. Vincent Valinducq explains. (Health and well-being).
Certain bacteria in the intestine may indicate an increased risk of Parkinson's disease early on, as shown by a study.
Observador
DnoticiasUniversity College London study reveals that intestinal microbiome analysis can identify Parkinson, years before the first symptoms. 638 people from different countries were examined.
Washington Times
The New York LedgerGut bacteria may flag Parkinson’s disease risk years before symptoms appear
The bacteria living in your gut may hold clues about your risk of developing Parkinson's disease long before any tremors or movement problems begin, according to a new study that researchers say could eventually lead to earlier screening and new prevention strategies.
Towards the development of a microbiome test, through the faeces, for the early diagnosis of Parkinson's, years before the onset of symptoms: the analysis of microorganisms in the intestinal flora can in fact reveal if a person is at increased risk of death... (ANSA)
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