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GLP-1 Drug Improved Motivation in Major Depressive Disorder
Researchers said oral semaglutide increased willingness to work for bigger rewards, with 72 participants showing lower perceived effort cost in a 16-week trial.
Summary by MedPage Today
2 Articles
2 Articles
GLP-1 Drug Improved Motivation in Major Depressive Disorder
(MedPage Today) -- Treatment with oral semaglutide (Rybelsus) significantly improved motivation measures in patients with major depressive disorder (MDD), according to a secondary analysis of a randomized trial. Among 72 participants with MDD...
·New York, United States
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expert reaction to RCT which looks at semaglutide and motivation in depression
A randomised controlled trial published in JAMA Psychiatry looks at semaglutide use and motivation in depression. Prof Ciara McCabe, Professor of Neuroscience, Psychopharmacology and Mental Health, University of Reading, said: “This is an interesting first step examining the effects of semaglutide on motivation (effort for reward task) and suggests that GLP-1 R agonists might increase motivation in MDD. However, the study is limited by its sm…
·London, United Kingdom
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