Gene Therapy Breakthrough Could Provide Hope for Millions Living with Chronic Pain

Gene therapy breakthrough could provide hope for millions living with chronic pain

A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of addiction from narcotics treatments, a breakthrough which could provide hope for the more than 50 million Americans living with chronic pain.

Chronic pain could be eased by uncoupling the sensory and emotional experiences

Researchers identify the neurons involved in the emotional distress associated with pain, and design a genetic approach that could soothe suffering without opioid drugs. Researchers identify the neurons involved in the emotional distress associated with pain, and design a genetic approach that could soothe suffering without opioid drugs.

Europe Moves Toward New Gene-Editing Rules as UK Leads Regulatory Shift

Europe’s approach to crop biotechnology is changing. New Genomic Techniques (NGTs) — including gene editing — are increasingly seen as tools to accelerate development of climate-resilient, nutrient-rich, and pest-resistant crops. But regulatory direction across the region remains uneven. The UK has already implemented a new legal framework, the EU is still negotiating its proposal, and Switzerland is developing a separate risk-based model. A pre…

Novel Gene Therapy Approach Targets Pain Centers in the Brain

More than 50 million Americans live with chronic pain. Drugs are currently available; however, close to 80% of the 600,000 deaths attributed to drug use in 2019 were related to opioids with about 25% of those deaths caused by opioid overdose. In addition, nearly half of Philadelphians who responded to a 2025 Pew survey reported knowing someone with opioid use disorder (OUD) and one-third knew someone who had died as the result of an overdose. Ta…

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A preclinical study uncovered a new gene therapy that targets pain centers in the brain while eliminating the risk of addiction from narcotics treatments, a breakthrough which could provide hope for the more than 50 million Americans living with chronic pain.