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CRISPR Uncovers Gene that Supercharges Vitamin D—and Stops Tumors in Their Tracks

JUL 18 – Inhibiting the SDR42E1 gene reduces cancer cell viability by 53% and may enable new precision oncology treatments, researchers say.

Summary by Science Daily
A gene called SDR42E1 has been identified as a key player in how our bodies absorb and process vitamin D. Researchers found that disabling this gene in colorectal cancer cells not only crippled their survival but also disrupted thousands of other genes tied to cancer and metabolism. This opens the door to highly targeted cancer therapies—by either cutting off vitamin D supply to tumors or enhancing the gene’s activity to boost health. The findin…

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Medical Xpress broke the news in on Friday, July 18, 2025.
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