Fungus Found to Reduce Inflammation in Crohn's Disease

Gut mucosal mycobiome profiling in Crohn’s disease uncovers an AMP-mediated anti-inflammatory effect of Cladosporium sphaerospermum - Nature Metabolism

Crohn’s disease (CD) is a subtype of inflammatory bowel disease that most commonly affects the terminal ileum and is associated with abnormal gut microbiome composition. However, the fungi of the small bowel mucosa and their metabolic functions, particularly protective ones, remain largely unexplored. We enrolled patients with CD and healthy individuals from three independent cohorts and conducted multi-omics profiling of the ileal mucosal mycob…

Advances in the research of intestinal fungi in Crohn's disease

This article reviews of the original research published by Wu et al in the World Journal of Gastroenterology, delving into the pivotal role of the gut microbiota in the pathogenesis of Crohn's disease (CD). Insights were gained from fecal microbiota ...

Cladosporium Fungus Identified as a Key Factor in Reducing Crohn’s Disease Inflammation

Researchers have identified a specific fungus, Cladospo […]

Cladosporium Fungi Reduce Inflammation in Crohn’s Disease

In a groundbreaking study that challenges long-held assumptions about the microbial inhabitants of our digestive tract, researchers have uncovered a vital role for a specific fungus in guarding against inflammation linked to Crohn’s disease (CD). This revelation not only deepens scientific understanding of the