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Fruit Fly Brain Model Walks, Feeds Inside a Computer

The emulation replicates 125,000 neurons and 50 million synapses to produce walking and feeding behaviors with 95% motor prediction accuracy, researchers said.

  • On Wednesday, Oct. 2, Eon Systems PBC demonstrated the world’s first embodied whole-brain emulation that drove behaviors in a simulated adult Drosophila melanogaster using NeuroMechFly v2 and the MuJoCo physics engine.
  • Built from electron‑microscopy of 7,000 slices, the FlyWire Consortium recently completed a fly wiring diagram, and Philip Shiu in 2024 published a connectome-based brain model with ML neurotransmitter predictions.
  • Validation shows the connectome‑based model predicted motor behavior with 95% accuracy, and the demonstration video emphasizes it is a biological connectome replica, not reinforcement‑learning approaches.
  • Eon Systems plans to scale from fly to mouse and build the largest connectome, advancing neuroscience and AI research communities.
  • Compared with earlier efforts, the demonstration marks a major scale jump from larval fly and nematode models and sparks debate on autonomous neural dynamics versus reinforcement‑learning flies.
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Berkeley broke the news in on Wednesday, October 2, 2024.
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