Fractionated Radiosurgery Extends Survival for Brain Metastasis Patients

Fractionated radiosurgery extends survival for brain metastasis patients

Delivering focused radiation therapy over three to five sessions after surgery for a large brain metastasis reduced the risk of cancer returning at the surgical site compared with delivering the radiation in a single session, according to the results of the Alliance for Clinical Trials in Oncology A071801 presented today at the plenary session of the American Society for Radiation Oncology in Boston.

Fractionated radiosurgery reduces cancer recurrence after surgery for large brain metastases

Delivering focused radiation therapy over three to five sessions after surgery for a large brain metastasis reduced the risk of cancer returning at the surgical site compared with delivering the radiation in a single session, according to the first randomized Phase III clinical trial directly comparing the approaches.

Fractionated SRS Should Be Standard of Care After Brain Metastasis Surgery

Ayal Aizer, MD, MHS, says Alliance A071801 supports fractionated SRS as standard after resection, with comparable radiation necrosis rates.

Study Finds Fractionated Radiosurgery Reduces Recurrence After Surgery for Brain Metastases, May Improve Survival

Mayo Clinic researchers led a multicenter study that found dividing radiation into several treatments, known as fractionated stereotactic radiosurgery, reduced the risk of cancer returning after surgery for brain metastases and was associated with improved survival compared with delivering radiation in a single treatment.