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For the First Time, a Genetically Modified Pig Lung Was Transplanted Into a Brain-Dead Man | News Channel 3-12

Researchers transplanted a gene-edited pig lung into a brain-dead man; the organ functioned for nine days before rejection and complications ended the trial, highlighting transplant challenges.

  • On May 15, 2024, researchers at the First Affiliated Hospital of Guangzhou Medical University transplanted a gene-edited pig lung into the recipient, marking the first known pig-to-human lung transplant attempt.
  • Amid a severe shortage of donor organs, over 103,000 people remain on organ donor waiting lists in the United States, prompting interest in xenotransplantation with prior pig kidneys, pig hearts, and last year's pig liver attempt in China.
  • The team reported the pig lung remained viable for nine days; by day one it showed fluid and inflammation, and by day three recipient antibodies began attacking it.
  • At the family's request, doctors terminated the experiment after complications, while study authors and the Guangzhou team stressed the procedure is not ready for clinical use and plan further transplants into brain-dead patients to test improvements.
  • Experts caution that despite this step, clinical use isn't likely in the near future, as lung xenotransplants require incremental progress and gene-editing advances continue to guide research scientists studying immune responses and gene edits.
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The genetically modified organ remained in the body of a brain dead patient for nine days and worked – with some difficulties

·Vienna, Austria
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In China, a group of surgeons managed to transplant a pig's lung into a human being for the first time, marking a great step forward in the ten-year research...

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Science News broke the news in United States on Monday, August 25, 2025.
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