For Legionella Bacteria, Taking Over a Cell Means Playing by Its Rules

For Legionella Bacteria, Taking Over a Cell Means Playing by Its Rules

Van Andel Institute scientists have discovered a new layer to the arms race between human cells and bacterial pathogens that infect them. The findings focus on RomA, a protein that Legionella bacteria release into host cells to create more favorable conditions. RomA works by altering how the host’s genes are controlled. The team discovered RomA can read and respond to the host cell’s existing epigenetic landscape — and that those same epigenetic signals determine where RomA can and cann

For Legionella bacteria, taking over a cell means playing by its rules – Van Andel Institute

Highlights Van Andel Institute scientists have discovered a new layer to the arms race between human cells and bacterial pathogens that infect them. The findings focus on RomA, a protein […] Van Andel Institute - Van Andel Institute transforms human health through groundbreaking biomedical research and cutting-edge science education.