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For adults with prediabetes, lifestyle intervention can lower risk of developing multiple chronic conditions

The benefit remained after diabetes was excluded, while metformin showed no significant reduction in risk over more than 20 years.

Summary by Medical Xpress
A clinical trial supported by the National Institutes of Health (NIH) found that adults with prediabetes assigned to a lifestyle intervention had a significantly lower risk of developing multiple chronic health conditions (known as multimorbidity) over time than those assigned to a placebo. This study, which followed participants for more than two decades, also found that participants assigned to receive metformin did not experience a statistica…

4 Articles

People with prediabetes who change their lifestyle are less likely to develop chronic diseases later in life than those who take a placebo. This is shown in an American study published in the journal JAMA. Even more striking: medication makes no major difference. If you have prediabetes, your doctor can suggest two things: adjusting your lifestyle or taking a pill (metformin). American researchers […] More science? Read the latest articles on Sc…

·Middelharnis, Netherlands (Kingdom of the)
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Medical Xpress broke the news on Monday, June 15, 2026.
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