FDA warns of ‘rare but severe itching’ after using popular allergy medications
- The FDA issued a warning on May 16, 2025, about rare but severe itching after stopping Zyrtec or Xyzal allergy medications in the US.
- This warning followed reports of 209 pruritus cases mostly involving patients who used these medicines daily for weeks or months.
- Numerous individuals reported experiencing severe itching shortly after discontinuing the medication, which significantly affected their daily activities and necessitated medical treatment.
- The FDA acknowledged that the evidence indicates a connection, highlighting that severe cases led to outcomes such as disability, the need for inpatient care, and mental health concerns including suicidal ideation or self-injury.
- The FDA cannot determine the exact likelihood of this reaction and urged patients to consult health professionals while requesting updated package warnings.
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FDA warns of 'rare but severe itching' after using popular allergy medications
(NEXSTAR) – Hundreds of people who stopped using allergy medications like Zyrtec and Xyzal noticed an uncomfortable new side effect, the U.S. Food and Drug Administration said in a warning issued this month. In "rare but severe" cases, and for unknown reasons, some who quit using the drugs became very itchy and had to seek medical help. "Reported cases were rare but sometimes serious, with patients experiencing widespread, severe itching that re…
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