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Everything Christina Applegate Has Said About Her Multiple Sclerosis Battle

The actress said MS has left her with 30 brain lesions, chronic pain and mobility limits, and she has been hospitalized more than 30 times.

Summary by E! News
Christina Applegate has vowed be frank about her struggles with multiple sclerosis—an autoimmune disease affecting the nervous system—no matter how painful it gets. Here's everything she's shared.

3 Articles

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Hollywood Life broke the news in Los Angeles, United States on Friday, April 17, 2026.
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