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Estrogen levels may dictate how the brain reacts to psychedelics, new animal study indicates

Summary by PsyPost
Psilocybin induces different behavioral responses in rats depending on their age and female reproductive cycles. Treating young rats with the drug, however, does not alter their behavior later in life. These outcomes indicate that psychedelic therapies may need to be customized for different patient demographics to ensure they work safely and effectively. The findings were published in the journal Neuropharmacology. Rates of mood disorders and a…

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PsyPost broke the news on Friday, May 15, 2026.
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