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Engineered Bacteria Can Consume Tumors From the Inside Out

University of Waterloo engineers added an oxygen-tolerance gene and quorum-sensing control to bacteria, improving tumor colonization and safety; pre-clinical trials are planned.

Summary by Phys.org
A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumors from the inside out. "Bacteria spores enter the tumor, finding an environment where there are lots of nutrients and no oxygen, which this organism prefers, and so it starts eating those nutrients and growing in size," said Dr. Marc Aucoin, a chemical engineering professor at Waterloo. "So, we are now…

8 Articles

Genetically modified bacteria target the oxygen-deprived tumor core and destroy the cancer from within, opening a new direction in therapy.

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News Medical broke the news in United States on Tuesday, February 24, 2026.
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