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Study Finds Toned Abs Linked to Lower Dementia Risk
A study of 1,164 participants found higher muscle mass and lower visceral fat linked to younger brain age, measured by MRI and AI, highlighting targets for brain health interventions.
- A multisite MRI study of 1,164 healthy participants from four sites found that higher muscle mass combined with a lower visceral fat-to-muscle ratio associates with a younger brain age.
- To better target Alzheimer's risk, researchers are using MRI and AI biomarkers to link muscle loss and visceral fat with brain aging and guide future trials to preserve muscle while lowering fat.
- Using whole-body MRI with T1-weighted sequences, the team quantified normalized muscle, visceral and subcutaneous fat, and computed brain-age estimates for participants with mean participant age 55.17 years.
- Researchers recommend preserving muscle while reducing visceral fat, cautioning that GLP-1 weight-loss drugs like Ozempic may accelerate muscle loss and require tailored dosing.
- The team noted that better brain health, as indicated in the study, may lower the risk for future brain diseases, such as Alzheimer's, Dr. Raji said.
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Total News Sources40
Leaning Left6Leaning Right5Center6Last UpdatedBias Distribution35% Left, 35% Center
Bias Distribution
- 35% of the sources lean Left, 35% of the sources are Center
35% Center
L 35%
C 35%
R 30%
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