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Novel mRNA Nanoparticle Exposes Hidden HIV in White Blood Cells
- Researchers at Melbourne's Peter Doherty Institute discovered a method to expose HIV hidden in white blood cells as reported in May 2025.
- This breakthrough addresses the main challenge that HIV hides inside resting CD4+ T cells, making it undetectable by the immune system and treatments.
- The team developed a novel lipid nanoparticle called LNP X that successfully delivers mRNA into these cells, a feat previously thought impossible.
- One dose of Tat-LNP X increased HIV RNA by 112-fold, with researchers describing this as a 'night and day difference' and reacting with gasps of 'wow.'
- Though the virus was exposed and not eliminated, this advance could lead to combining reactivation with cell-killing therapies, marking progress toward an HIV cure.
50 Articles
50 Articles
Covid vaccine tech could one day lead to a cure for HIV
The technology that powered Covid vaccines may also lead scientists to a cure for HIV. Using mRNA, Australian researchers said they were able to trick the virus to come out of hiding, a crucial step in ridding the body of…
A link to HIV could soon become a reality of current times. Researchers have found a new way to force the virus no longer to hide in human cells, is shown in a report The Guardian. It is based on ARNm technology, which becomes known worldwide during the Covid-19 pandemic, being used in vaccines produced by Moderna and Pfizer/BioNTech.
Australian scientists claim to have found a new way to attack the HIV reservoir to force it "out of its hiding place."
Doctors Near HIV Cure with ‘Previously Impossible’ Discovery: ‘We Have Never Seen Anything Close to As Good’ - News Addicts
An estimated 39 million people around the world are living with HIV — and, while treatment options can ensure they have long, healthy lives, there is no known cure. Antiretroviral therapy (ART) — the most effective current treatment — can reduce HIV levels in the body so low the virus is almost undetectable. However, the […] The post Doctors Near HIV Cure with ‘Previously Impossible’ Discovery: ‘We Have Never Seen Anything Close to As Good’ appe…
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