DNA Sensors Inspired by the Human Nose Detect Early-Stage Cancer

DNA Sensors Inspired by the Human Nose Detect Early-Stage Cancer

Scientists have developed a liquid biopsy platform that detects multiple types of cancer with a single test by analyzing complex patterns in blood samples, using a strategy similar to the human sense of smell. In a study published in Science Advances, the test was able to distinguish liver, lung, and ovarian cancers from healthy samples, achieving 92% sensitivity in early-stage lung cancer detection.  “Our system combines accurate detection with…

Integrating structurally defined DNA-carbon nanotube sensors with machine learning for cancer detection

Abstract Liquid biopsy is a promising, noninvasive approach for cancer detection, but current methods often trade off accuracy, operability, and cost. To address these limitations, we introduce an artificial perception system (APS) for liquid biopsy that combines a structurally defined DNA-carbon nanotube sensor array with machine learning (ML) models. The array produces multichannel fluorescence fingerprints from serum, which are decoded by ML …