DNA Methylation Epitypes of Burkitt Lymphoma with Distinct Molecular and Clinical Features - Science in Vancouver
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DNA Methylation Epitypes of Burkitt Lymphoma with Distinct Molecular and Clinical Features - Science in Vancouver
The genetic subtypes of Burkitt lymphoma have been defined, but the role of epigenetics remains to be comprehensively characterized. We searched genomic DNA from 218 patients across four continents for recurrent DNA methylation patterns and their associations with clinical and molecular features. We identified DNA methylation patterns that were not fully explained by the Epstein–Barr virus status or mutation status, leading to two epitypes descr…
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