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Study Finds Denisovan MUC19 Variant Concentrated in Indigenous American Ancestry
One in three people of Mexican ancestry carry a Denisovan gene variant linked to Indigenous American heritage, which may have aided adaptation to diverse American ecosystems.
- University of Colorado Boulder researchers report Denisovan DNA in early Americans and published their findings in the journal Science.
- Geneticists note Denisovans interbred with Neanderthals and humans, shaping modern genomes; first identified 15 years ago, Denisovans ranged from Russia to Oceania before extinction.
- Researchers discovered one in three people of Mexican ancestry carry a Denisovan-derived MUC19 gene variant, which appears surrounded by Neanderthal DNA in Indigenous American populations.
- Fernando Villanea said, `In terms of evolution, this is an incredible leap`, highlighting biological and cultural changes over 'over 20,000 years'.
- Why the Denisovan variant is concentrated in the Americas remains unclear, underlining gaps in current knowledge about ancient admixture, Villanea said.
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