Discovery reveals how neuronal ion channels store molecular memory
7 Articles
7 Articles
Molecular dynamics simulations show how potassium passes through an ion channel at atomic resolution
They are literally channels for communication: Pore-forming proteins in living cells, termed ion channels, are embedded in the outer membrane of almost all cell types and play a crucial role in the body's various communication systems. Blood, immune, and liver cells communicate via these channels. Nerve cells use them to transmit electrical signals to other cells.
Brain's Gatekeepers Remember Signals to Shape Long-Term Memory
Summary: A new study reveals how calcium ion channels in the brain don’t just relay signals—they remember them. Researchers discovered that CaV2.1 channels at synapses can adopt nearly 200 shapes based on electrical activity, effectively entering a “memory state” that weakens signal transmission. These brief molecular memories accumulate over time, leading to long-term synaptic changes essential for learning and memory formation. Like a clutch i…
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