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DePaul Blue Demons at St. John's Red Storm Odds, Picks and Predictions

St. John’s opens Big East play at Carnesecca Arena aiming to defend its title while DePaul seeks to extend a three-game winning streak, with St. John’s averaging 88.9 points per game.

  • On Tuesday, St. John's Red Storm begins its Big East title defense by hosting DePaul Blue Demons at Carnesecca Arena in the teams' first conference meeting this season.
  • Last season St. John's went 21-2 against Big East opponents and claimed both conference titles, earning its first regular-season title since 1985 and first tournament crown since 2000.
  • DePaul Blue Demons score 77.4 points per game, shooting 45.9%, with Bryce Hopkins at 52.4%, CJ Gunn 44.7%, and Oziyah Sellers hitting 46.3% from 3.
  • DePaul Blue Demons seek to extend a three-game win streak on Tuesday while holding a 1-0 road record, yet remain 0-4 against St. John's Red Storm since Rick Pitino became head coach.
  • After this one-off at Carnesecca, St. John's Red Storm will play two more non-conference games before its Big East slate and host nine conference games at Madison Square Garden.
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DePaul Blue Demons face the No. 22 St. John's Red Storm, aim for 4th straight win

DePaul will try to prolong its three-game win streak with a victory over No. 22 St. John's. The teams play Tuesday for the first time this season. St.

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KVUE broke the news in Austin, United States on Monday, December 15, 2025.
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