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Decoding genotypic antimicrobial resistance amongst colistin-resistant Gram-negative bloodstream isolates at a South African academic healthcare facility
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Decoding genotypic antimicrobial resistance amongst colistin-resistant Gram-negative bloodstream isolates at a South African academic healthcare facility
This study analyzed colistin-resistant Gram-negative bacteria causing bloodstream infections in paediatric patients at a tertiary hospital in Soweto, South Africa (2023–2024). Using whole-genome sequencing, researchers examined resistant isolates of Klebsiella pneumoniae, Acinetobacter baumannii, and Escherichia coli. The results revealed high-risk global clones of K. pneumoniae carrying major resistance genes (blaNDM and blaOXA-48), with geneti…
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